Nombre del producto:Mal-amido-PEG8-val-gly-PAB-OH

IUPAC Name:1-[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido]-N-[(1S)-1-[({[4-(hydroxymethyl)phenyl]carbamoyl}methyl)carbamoyl]-2-methylpropyl]-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-amide

CAS:2353409-52-4
Fórmula molecular:C40H63N5O15
Pureza:95%+
Número de catálogo:CM339035
Peso molecular:853.96

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CM339035-10mg in stock ŤŤŤľ

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Detalles del producto

Núm. De CAS :2353409-52-4
Fórmula molecular:C40H63N5O15
Punto de fusión:-
Código de sonrisas:O=C(CNC([C@H](C(C)C)NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN(C1=O)C(C=C1)=O)=O)=O)=O)NC2=CC=C(CO)C=C2
Densidad:
Número de catálogo:CM339035
Peso molecular:853.96
Punto de ebullición:
Nº Mdl:
Almacenamiento:

Category Infos

ADC-Linkers
The ADC linker is one of the three main components of antibody drug conjugates (ADCs), linking the antibody to the effective drug (payload) through chemical bonds. ADC linkers play a key role in determining the overall success of antibody drug conjugates. One of the major challenges in developing safe and effective ADC drugs is to assemble an ideal chemical linker between the cytotoxic payload and the mAb. Well-designed ADC linkers can help the selective delivery of antibodies at the tumor site and the accurate release of cytotoxic drugs.
Cleavable linkers
Cleavable linkers rely on the inherent properties of a cell’s cytoplasmic compartments for selective release of the cytotoxic drug.
PEG linkers
PEG Reagents are chemically functionalized polyethylene glycol (PEG) linkers.PEG linkers are highly water-soluble and non-immunogenic linkers.
Maleimides
Thiol-maleimide is a bifunctional chemical compound that is commonly used in bioconjugation reactions to crosslink two molecules via the thiol (-SH) groups.