Nombre del producto:1-((2-(Furan-2-yl)imidazo[1,2-a]pyridin-3-yl)methyl)piperidine-4-carboxylic acid

IUPAC Name:1-{[2-(furan-2-yl)imidazo[1,2-a]pyridin-3-yl]methyl}piperidine-4-carboxylic acid

CAS:904817-29-4
Fórmula molecular:C18H19N3O3
Pureza:97%
Número de catálogo:CM271194
Peso molecular:325.37

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Detalles del producto

Núm. De CAS :904817-29-4
Fórmula molecular:C18H19N3O3
Punto de fusión:-
Código de sonrisas:O=C(C1CCN(CC2=C(C3=CC=CO3)N=C4C=CC=CN42)CC1)O
Densidad:
Número de catálogo:CM271194
Peso molecular:325.37
Punto de ebullición:
Nº Mdl:
Almacenamiento:

Category Infos

Furans
Furan is a cyclic flammable liquid compound C4H4O that is obtained from wood oils of pines or made synthetically and is used especially in organic synthesis. Furan is aromatic because a pair of lone pair electrons of the oxygen atom in its molecule forms a large π bond in the plane of the conjugated orbital, making a total of 6 electrons in the plane of the conjugated plane, conforming to the 4n+2 structure. Aromaticity makes furan have the property of easy substitution and difficult addition. The other lone pair of electrons in oxygen stretches out. The oxygen atom itself conforms to sp2 hybridization. Due to the presence of the aromatic ring, the chemical behavior of furan is not very similar to that of other unsaturated heterocycles. The oxygen in the aromatic ring has an electron-donating effect, so the electrophilic substitution reactivity of furan is stronger than that of benzene.
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Piperidines
Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
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Imidazopyridines
With four imidazopyridine-containing drugs and one pyrazolopyridine-containing drug on the market, bicyclic pyridines containing ring-junction nitrogen are privileged structures in medicinal chemistry. With two nitrogen atoms with potential to serve as hydrogen bond acceptors, imidazopyridines and pyrazolopyridines may boost binding to target proteins and elevate potency. In addition, these structures have found utility in FBDD, covalent inhibitors, reducing metabolic liabilities, and creating novel chemical space and intellectual properties. With many of the advanced intermediates now commercially available, they will find more and more applications in drug discovery.
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