Nombre del producto:2-Ethylbutyric Acid

IUPAC Name:2-ethylbutanoic acid

CAS:88-09-5
Fórmula molecular:C6H12O2
Pureza:95%+
Número de catálogo:CM394240
Peso molecular:116.16

Unidad de embalaje Stock disponible Precio($) Cantidad
CM394240-500mg in stock Ţư
CM394240-1g in stock źŢ

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Detalles del producto

Núm. De CAS :88-09-5
Fórmula molecular:C6H12O2
Punto de fusión:-
Código de sonrisas:CCC(CC)C(O)=O
Densidad:
Número de catálogo:CM394240
Peso molecular:116.16
Punto de ebullición:
Nº Mdl:
Almacenamiento:

Column Infos

KB-0742
Kronos Bio announces the first patient dosed in an expansion cohort with KB-0742 at a dose of 80mg given on a four-days-on, three-days-off schedule. This expansion cohort is enrolling platinum-resistant patients with high-grade serous ovarian cancer (HGSOC). Many cancers exhibit transcriptional deregulation, often characterized by gene amplifications of MYC family oncogene. Targeting the transcription elongation cofactor, cyclin-dependent kinase 9 (CDK9) has emerged as a therapeutic strategy to disrupt MYC oncogenic activity.
KB-0742 is an oral highly selective CDK9 inhibitor designed for the treatment of patients with MYC-amplified and other transcriptionally addicted relapsed or refractory solid tumors, including ovarian, lung, and triple-negative breast cancers.