Thiophene is a five-membered heterocyclic compound containing a sulfur heteroatom with the molecular formula C4H4S. Thiophene is aromatic and is very similar to benzene; electrophilic substitution reaction is easier than benzene, and it is mainly substituted at the 2-position. Thiophene ring system has certain stability to oxidant.
Isoindolinones are ubiquitous structural motifs in natural products and pharmaceuticals. Isoindolinones are precursors to other valuable building blocks.
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