Nombre del producto:8-chloro-4-(dimethylaminomethylene)-1-(2-fluoro-6-methoxy-phenyl)-3H-2-benzazepin-5-one

IUPAC Name:8-chloro-4-[(dimethylamino)methylidene]-1-(2-fluoro-6-methoxyphenyl)-4,5-dihydro-3H-2-benzazepin-5-one

CAS:869367-33-9
Fórmula molecular:C20H18ClFN2O2
Pureza:95%+
Número de catálogo:CM1018162
Peso molecular:372.82

Unidad de embalaje Stock disponible Precio($) Cantidad
CM1018162-100mg in stock ȬɅŴ
CM1018162-250mg in stock ŴƦƦ
CM1018162-500mg 1-2 Weeks NJƦƦNJ
CM1018162-1g 1-2 Weeks NJȁƦƦ
CM1018162-5g 1-2 Weeks ƀȁƦƦ

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Detalles del producto

Núm. De CAS :869367-33-9
Fórmula molecular:C20H18ClFN2O2
Punto de fusión:-
Código de sonrisas:COC1=CC=CC(F)=C1C1=NCC(=CN(C)C)C(=O)C2=CC=C(Cl)C=C12
Densidad:
Número de catálogo:CM1018162
Peso molecular:372.82
Punto de ebullición:
Nº Mdl:
Almacenamiento:

Column Infos

Alisertib
Puma Biotechnology announced the initiation of its ALISertib in CAncer (ALISCA-Lung1) Phase II trial of alisertib monotherapy for the treatment of patients with extensive stage small cell lung cancer. The ALISCA-Lung1 trial will enroll up to 60 patients with extensive stage small cell lung cancer who have progressed on or after first-line platinum-based chemotherapy and immunotherapy. The primary endpoint of the trial is objective response rate, with secondary endpoints of duration of response, disease control rate, progression-free survival and overall survival. Based upon the outcomes of the study, Puma anticipates meeting with the FDA to explore the potential for an accelerated approval pathway for alisertib in small cell lung cancer. Alisertib is an orally active and selective Aurora A kinase inhibitor, which binds to Aurora A kinase resulting in mitotic spindle abnormalities, mitotic accumulation.
Chemenu has been working to develop more compounds for drug discovery. Here are the building blocks we can provide.