Nombre del producto:N3-C4-NHS ester

IUPAC Name:2,5-dioxopyrrolidin-1-yl 5-azidopentanoate

CAS:478801-48-8
Fórmula molecular:C9H12N4O4
Pureza:95%+
Número de catálogo:CM339187
Peso molecular:240.22

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Detalles del producto

Núm. De CAS :478801-48-8
Fórmula molecular:C9H12N4O4
Punto de fusión:-
Código de sonrisas:O=C(ON1C(CCC1=O)=O)CCCCN=[N+]=[N-]
Densidad:
Número de catálogo:CM339187
Peso molecular:240.22
Punto de ebullición:
Nº Mdl:
Almacenamiento:

Category Infos

ADC-Linkers
The ADC linker is one of the three main components of antibody drug conjugates (ADCs), linking the antibody to the effective drug (payload) through chemical bonds. ADC linkers play a key role in determining the overall success of antibody drug conjugates. One of the major challenges in developing safe and effective ADC drugs is to assemble an ideal chemical linker between the cytotoxic payload and the mAb. Well-designed ADC linkers can help the selective delivery of antibodies at the tumor site and the accurate release of cytotoxic drugs.
N-Hydroxysuccinimide (NHS)
N-Hydroxysuccinimide
Azides
Azides are used in click chemistry, such as copper-catalyzed azide-alkyne [3+2] cycloaddition (CuAAC),and strain-promoted [3+2] azide-alkyne cycloaddition reaction (SPAAC).
Non-cleavable linkers
Noncleavable linkers consist of stable bonds that resist proteolytic degradation and provide higher stability than the cleavable linkers.

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