Nombre del producto:5'-Bromo-1',2'-dihydrospiro[cyclohexane-1,3'-indole]-2'-one

IUPAC Name:5'-bromo-1',2'-dihydrospiro[cyclohexane-1,3'-indol]-2'-one

CAS:304468-42-6
Fórmula molecular:C13H14BrNO
Pureza:97%
Número de catálogo:CM139022
Peso molecular:280.17

Unidad de embalaje Stock disponible Precio($) Cantidad
CM139022-250mg in stock ȌƤ
CM139022-1g in stock ȦȷƋ

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Detalles del producto

Núm. De CAS :304468-42-6
Fórmula molecular:C13H14BrNO
Punto de fusión:-
Código de sonrisas:O=C(C12CCCCC1)NC3=C2C=C(Br)C=C3
Densidad:
Número de catálogo:CM139022
Peso molecular:280.17
Punto de ebullición:
Nº Mdl:MFCD12964079
Almacenamiento:Store at 2-8°C.

Category Infos

Cyclohexanes
Cyclohexane is an organic compound with a chemical formula C6H12. It is a colorless liquid with a pungent odor, insoluble in water, and soluble in most organic solvents such as ethanol, ether, benzene, and acetone. Cyclohexyl fragments are a common structure in both natural and synthetic drugs. It can be used as both core structure and part of achiral side chain.
Indolinones
Indolinone derivatives have in common the presence of a hydrogen bond between the C-2 carbonyl and a hydrogen donor in a side chain, generally a pyrrole ring. Indolinone displays very promising antitumor properties by inhibiting various kinase families.

Column Infos

Spiro Compounds
A spiro compound is a polycyclic compound in which two monocyclic rings share one carbon atom; the shared carbon atom is called a spiro atom. Spiro compounds have rigid structures, stable structures, and have special properties that general organic compounds do not possess, such as anomeric effect, spiro conjugation and spiro hyperconjugation. Compared with the monocyclic structure or the planar aromatic structure, the spiro structure has a larger three-dimensional structure; the heterocyclic spiro structure is also regarded as the biological isostere of some groups, which can change the drug to a certain extent. The water solubility, lipophilicity, dominant conformation and ADMET properties of the molecule make the optimized lead molecule easier to drug. Therefore, spiro compounds occupy a very important position in drug development.

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