cas 28875-17-4|| where to buy N-Boc-L-alanine Methyl Ester

Nombre del producto:N-Boc-L-alanine Methyl Ester

IUPAC Name:methyl (2S)-2-{[(tert-butoxy)carbonyl]amino}propanoate

Unidad de embalaje	Stock disponible	Precio($)
CM119523-25g	1-2 Weeks	ƋǕ
CM119523-100g	3-4 Weeks	ƱǕɐ

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: Núm. De CAS :28875-17-4; Fórmula molecular:C9H17NO4; Punto de fusión:-; Código de sonrisas:C[C@@H](C(OC)=O)NC(OC(C)(C)C)=O; Densidad:

: Número de catálogo:CM119523; Peso molecular:203.24; Punto de ebullición:; Nº Mdl:MFCD00038513; Almacenamiento:

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: PF-06648671; The Journal of Medicinal Chemistry recently publishes an article titled, “Discovery of Clinical Candidate PF-06648671: A Potent γ-Secretase Modulator for the Treatment of Alzheimer’s Disease”. Amyloid β-peptide (Aβ) accumulation is one of the key hallmarks of Alzheimer’s disease (AD). γ-secretase cleaves the amyloid precursor protein (APP) into pathologically relevant Aβs, and has been widely studied as a potential target for the treatment of AD.
Pfizer‘s PF-06648671 is a Gamma secretase modulator (GSM) targeting APP processing. It is found to have excellent central exposure in human and robust reduction of amyloidogenic forms (Aβ42) in cerebrospinal fluid (CSF).