cas 2869955-58-6|| where to buy 5-hydroxy-6-methyl-pyrimidine-4-carboxylic acid

Nombre del producto:5-hydroxy-6-methyl-pyrimidine-4-carboxylic acid

IUPAC Name:5-hydroxy-6-methylpyrimidine-4-carboxylic acid

Unidad de embalaje	Stock disponible	Precio($)
CM1051318-100mg	in stock	ǯǕǕ
CM1051318-250mg	in stock	ňŢŔ

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: Núm. De CAS :2869955-58-6; Fórmula molecular:C6H6N2O3; Punto de fusión:-; Código de sonrisas:CC1=NC=NC(C(O)=O)=C1O; Densidad:

: Número de catálogo:CM1051318; Peso molecular:154.13; Punto de ebullición:; Nº Mdl:; Almacenamiento:

: Pyrimidines; Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.

: HRO761; Novartis'HRO761 is an oral allosteric inhibitor targeting WRN helicase, aimed at treating microsatellite instability (MSI) or deficient mismatch repair (dMMR) tumors. WRN has emerged as a critical synthetic lethal target in MSI cancers, which are common in colorectal, gastric, endometrial, and ovarian cancers. Although MSI cancers show a high response rate to immune checkpoint inhibitors, many patients develop resistance. By acting on WRN, HRO761 may be able to stop the growth of the cancer.
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