Nombre del producto:3-methyloxetane-3-carboxylic acid

IUPAC Name:3-methyloxetane-3-carboxylic acid

Fórmula molecular:C5H8O3
Número de catálogo:CM104067
Peso molecular:116.12

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Detalles del producto

Núm. De CAS :28562-68-7
Fórmula molecular:C5H8O3
Punto de fusión:-
Código de sonrisas:CC1(COC1)C(O)=O
Número de catálogo:CM104067
Peso molecular:116.12
Punto de ebullición:
Nº Mdl:MFCD09842435

Category Infos

Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.

Column Infos

Alicyclic Heterocycles
When the ends of the chains are joined together into a ring, cyclic compounds result; such substances often are referred to as carbocyclic or alicyclic compounds. Substitution of one or more of the ring carbon atoms in the molecules of a carbocyclic compound with a heteroatom gives a heterocyclic compound.