Nombre del producto:(R)-3-Pyrrolidinol

IUPAC Name:(3R)-pyrrolidin-3-ol

CAS:2799-21-5
Fórmula molecular:C4H9NO
Pureza:97%
Número de catálogo:CM116633
Peso molecular:87.12

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Detalles del producto

Núm. De CAS :2799-21-5
Fórmula molecular:C4H9NO
Punto de fusión:-
Código de sonrisas:O[C@H]1CNCC1
Densidad:
Número de catálogo:CM116633
Peso molecular:87.12
Punto de ebullición:224.7°C at 760 mmHg
Nº Mdl:MFCD00145220
Almacenamiento:Keep in dark place, inert atmosphere, store at 2-8°C.

Category Infos

Pyrrolidines
Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.

Column Infos

Pyrroles
Pyrrole is a five membered heterocyclic compound with the molecular formula of C4H5N. Pyrrole has a ring composed of four carbon atoms and one nitrogen atom. Pyrrole is easy to polymerize in the air. Pyrrole is the parent compound of many important biological substances (such as bile pigment, porphyrin and chlorophyll). Pyrrole scaffolds are widely used in biological and pharmaceutical fields. Pyrrole is a special heterocyclic scaffold, which exists in many natural products, drug molecules and pesticides, and has shown its application in materials science.
Asciminib
Novartis Scemblix® FDA approved in newly diagnosed CML, offering superior efficacy, and favorable safety and tolerability profile. Scemblix now approved for newly diagnosed and previously treated CML, allowing four times the patients access to potential new standard of care.
Scemblix is an orally available tyrosine kinase inhibitor that works by blocking the BCR-ABL1 fusion protein, a known hallmark of certain leukemias. The drug was first approved for CML three years ago, winning two indications. The first is for the treatment of Philadelphia chromosome-positive, chronic phase CML, for which the drug was given accelerated approval. The second is a full approval for the same patient population, with the additional specification that they carry the T315I mutation.