Nombre del producto:N-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]-8-(hydroxyamino)-8-oxo-octanamide

IUPAC Name:N'-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]-N-hydroxyoctanediamide

CAS:2758388-38-2
Fórmula molecular:C21H24N4O7
Pureza:95%
Número de catálogo:CM1077511
Peso molecular:444.44

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Detalles del producto

Núm. De CAS :2758388-38-2
Fórmula molecular:C21H24N4O7
Punto de fusión:-
Código de sonrisas:ONC(=O)CCCCCCC(=O)NC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1
Densidad:
Número de catálogo:CM1077511
Peso molecular:444.44
Punto de ebullición:
Nº Mdl:
Almacenamiento:

Category Infos

PROTAC-E3 Ligase Ligands
Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.