Código de sonrisas:O=C(O)C1=CC=C2C=C(C3=CC(C4=CC5=CC=C(C(O)=O)C=C5C=C4)=CC6=C3NC7=C6C=C(C8=CC9=CC=C(C(O)=O)C=C9C=C8)C=C7C%10=CC%11=CC=C(C(O)=O)C=C%11C=C%10)C=CC2=C1
Carbazoles are an important class of nitrogen-containing heterocycles with a planar tricyclic skeleton consisting of two benzene rings fused on both sides of the central pyrrole ring, with a large aromatic system and a central nitrogen atom, showing broad of electron delocalization. The structure of this compound is based on the indole structure, but in which a second benzene ring is fused to a five-membered ring at positions 2-3 of the indole. Carbazole structural motifs are widely found in, but not limited to, a large number of natural alkaloids of plant or bacterial origin. Since many of these alkaloids are medically useful, exhibit a fairly wide range of biological activities (anticancer, anti-HIV, antibacterial, anti-Alzheimer's disease, anticoagulant, analgesic, antiepileptic, antidiabetic, antioxidant, etc.). Medicinal chemistry also uses carbazole motifs in synthetic drugs to combat hypertension, heart disease, and hepatitis C virus replication.
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