Nombre del producto:Ald-Ph-amido-PEG3-NHS ester

IUPAC Name:2,5-dioxopyrrolidin-1-yl 3-[2-(2-{2-[(4-formylphenyl)formamido]ethoxy}ethoxy)ethoxy]propanoate

CAS:2101206-32-8
Fórmula molecular:C21H26N2O9
Pureza:95%+
Número de catálogo:CM339002
Peso molecular:450.44

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Detalles del producto

Núm. De CAS :2101206-32-8
Fórmula molecular:C21H26N2O9
Punto de fusión:-
Código de sonrisas:O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCNC(C2=CC=C(C=O)C=C2)=O
Densidad:
Número de catálogo:CM339002
Peso molecular:450.44
Punto de ebullición:
Nº Mdl:
Almacenamiento:

Category Infos

ADC-Linkers
The ADC linker is one of the three main components of antibody drug conjugates (ADCs), linking the antibody to the effective drug (payload) through chemical bonds. ADC linkers play a key role in determining the overall success of antibody drug conjugates. One of the major challenges in developing safe and effective ADC drugs is to assemble an ideal chemical linker between the cytotoxic payload and the mAb. Well-designed ADC linkers can help the selective delivery of antibodies at the tumor site and the accurate release of cytotoxic drugs.
PEG linkers
PEG Reagents are chemically functionalized polyethylene glycol (PEG) linkers.PEG linkers are highly water-soluble and non-immunogenic linkers.
N-Hydroxysuccinimide (NHS)
N-Hydroxysuccinimide
Non-cleavable linkers
Noncleavable linkers consist of stable bonds that resist proteolytic degradation and provide higher stability than the cleavable linkers.
Hydrazones/Aldehydes/Ketones
A hydrazine or hydrazide group is able to react with an aldehyde or ketone to form a dehydration product, called a hydrazone.

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