Nombre del producto:(S)-(3-(8-Amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)piperidin-1-yl)(3-methyloxetan-3-yl)methanone

IUPAC Name:1-bromo-3-[(3S)-1-(3-methyloxetane-3-carbonyl)piperidin-3-yl]imidazo[1,5-a]pyrazin-8-amine

CAS:1956434-97-1
Fórmula molecular:C16H20BrN5O2
Pureza:97%
Número de catálogo:CM285801
Peso molecular:394.27

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Detalles del producto

Núm. De CAS :1956434-97-1
Fórmula molecular:C16H20BrN5O2
Punto de fusión:-
Código de sonrisas:O=C(N1C[C@@H](C2=NC(Br)=C3C(N)=NC=CN32)CCC1)C4(C)COC4
Densidad:
Número de catálogo:CM285801
Peso molecular:394.27
Punto de ebullición:
Nº Mdl:
Almacenamiento:

Category Infos

Piperidines
Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
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Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.
Imidazopyrazines
In addition to the nitrogen-based heterocycles presented so far, a number of others nitrogen-based scaffolds have also been reported as promising agents for GBM treatment, including pyrazolo-triazole, imidazotetrazine, piperidine, purine, imidazopyrazine, pyrazole, triazole among others.