Nombre del producto:5-(tert-Butoxycarbonyl)-5-azaspiro[2.3]hexane-4-carboxylic acid

IUPAC Name:5-[(tert-butoxy)carbonyl]-5-azaspiro[2.3]hexane-4-carboxylic acid

CAS:1822561-92-1
Fórmula molecular:C11H17NO4
Pureza:97%
Número de catálogo:CM212209
Peso molecular:227.26

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Detalles del producto

Núm. De CAS :1822561-92-1
Fórmula molecular:C11H17NO4
Punto de fusión:-
Código de sonrisas:O=C(C(N(C(OC(C)(C)C)=O)C1)C21CC2)O
Densidad:
Número de catálogo:CM212209
Peso molecular:227.26
Punto de ebullición:
Nº Mdl:MFCD24533647
Almacenamiento:

Category Infos

Spiro Compounds
A spiro compound is a polycyclic compound in which two monocyclic rings share one carbon atom; the shared carbon atom is called a spiro atom. Spiro compounds have rigid structures, stable structures, and have special properties that general organic compounds do not possess, such as anomeric effect, spiro conjugation and spiro hyperconjugation. Compared with the monocyclic structure or the planar aromatic structure, the spiro structure has a larger three-dimensional structure; the heterocyclic spiro structure is also regarded as the biological isostere of some groups, which can change the drug to a certain extent. The water solubility, lipophilicity, dominant conformation and ADMET properties of the molecule make the optimized lead molecule easier to drug. Therefore, spiro compounds occupy a very important position in drug development.
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Azetidines
Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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