Nombre del producto:tert-Butyl 4-(1-hydroxycyclopropyl)piperidine-1-carboxylate

IUPAC Name:tert-butyl 4-(1-hydroxycyclopropyl)piperidine-1-carboxylate

Fórmula molecular:C13H23NO3
Número de catálogo:CM101768
Peso molecular:241.33

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Detalles del producto

Núm. De CAS :1785348-09-5
Fórmula molecular:C13H23NO3
Punto de fusión:-
Código de sonrisas:O=C(N1CCC(C2(O)CC2)CC1)OC(C)(C)C
Número de catálogo:CM101768
Peso molecular:241.33
Punto de ebullición:
Nº Mdl:MFCD28357550

Category Infos

Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
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Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

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