Nombre del producto:Methanesulfonic acid,trifluoro-,(3R)-3-(dicyclobutylamino)-8-fluoro-3,4-dihydro-2H-1-benzopyran-5-yl ester(9CI)

IUPAC Name:(3R)-3-(dicyclobutylamino)-8-fluoro-3,4-dihydro-2H-1-benzopyran-5-yl trifluoromethanesulfonate

CAS:169759-09-5
Fórmula molecular:C18H21F4NO4S
Pureza:95%+
Número de catálogo:CM665074
Peso molecular:423.42

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Detalles del producto

Núm. De CAS :169759-09-5
Fórmula molecular:C18H21F4NO4S
Punto de fusión:-
Código de sonrisas:FC1=CC=C(OS(=O)(=O)C(F)(F)F)C2=C1OC[C@@H](C2)N(C1CCC1)C1CCC1
Densidad:
Número de catálogo:CM665074
Peso molecular:423.42
Punto de ebullición:
Nº Mdl:
Almacenamiento:

Category Infos

Pyrans
Pyrans are an important class of six-membered heterocyclic compounds, non-aromatic rings, composed of five carbon atoms and one oxygen atom, and contain two double bonds. The molecular formula of pyran is C5H6O, and there are two isomers. Pyrans, together with benzo derivatives, form scaffolds for a variety of drug applications, many of which are approved and promising candidates in clinical trials and recently isolated bioactive natural products.
Fluorinated Compounds
Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.
Cyclobutanes
The molecular structure of cyclobutane has four carbon atoms, and its four carbon atoms are not in the same plane, which is the folded conformation of cyclobutane. Cyclobutane itself is not of commercial or biological interest, but more complex derivatives are important in biology and biotechnology. Currently, nine FDA-approved drugs contain the cyclobutane structure. From the perspective of therapeutic areas, cyclobutyl drugs are mainly distributed in popular areas such as tumors, neurological diseases, infectious diseases, endocrine and metabolic diseases.