Nombre del producto:5-Bromo-2',3',5',6'-tetrahydrospiro[indoline-3,4'-pyran] hydrochloride

IUPAC Name:5-bromo-1,2-dihydrospiro[indole-3,4'-oxane] hydrochloride

CAS:1609266-05-8
Fórmula molecular:C12H15BrClNO
Pureza:97%
Número de catálogo:CM210646
Peso molecular:304.61

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Detalles del producto

Núm. De CAS :1609266-05-8
Fórmula molecular:C12H15BrClNO
Punto de fusión:-
Código de sonrisas:BrC1=CC2=C(NCC23CCOCC3)C=C1.[H]Cl
Densidad:
Número de catálogo:CM210646
Peso molecular:304.61
Punto de ebullición:
Nº Mdl:
Almacenamiento:

Category Infos

Spiro Compounds
A spiro compound is a polycyclic compound in which two monocyclic rings share one carbon atom; the shared carbon atom is called a spiro atom. Spiro compounds have rigid structures, stable structures, and have special properties that general organic compounds do not possess, such as anomeric effect, spiro conjugation and spiro hyperconjugation. Compared with the monocyclic structure or the planar aromatic structure, the spiro structure has a larger three-dimensional structure; the heterocyclic spiro structure is also regarded as the biological isostere of some groups, which can change the drug to a certain extent. The water solubility, lipophilicity, dominant conformation and ADMET properties of the molecule make the optimized lead molecule easier to drug. Therefore, spiro compounds occupy a very important position in drug development.
Spiro And Bicyclic Compound
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Tetrahydropyrans
Tetrahydropyran is an organic compound consisting of a saturated six-membered ring containing five carbon atoms and one oxygen atom. Tetrahydropyrans are common structural motifs in natural products and synthetic therapeutic molecules. In nature, these six-membered oxygen heterocycles are usually assembled by intramolecular reactions, including oxygen Michael addition or ring opening of epoxy alcohols. In fact, polyether natural products have been particularly extensively studied for their fascinating structures and important biological properties; these are often formed through endoselective epoxy open cascades.

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