Nombre del producto:Acetamide, N-[2-[5-[[4-chloro-5-(trifluoromethyl)-2-pyrimidinyl]amino]-1,3-dihydro-1,3-ethano-2H-isoindol-2-yl]-2-oxoethyl]-

IUPAC Name:N-{2-[(1R,8S)-4-{[4-chloro-5-(trifluoromethyl)pyrimidin-2-yl]amino}-11-azatricyclo[6.2.1.0²,⁷]undeca-2(7),3,5-trien-11-yl]-2-oxoethyl}acetamide

CAS:1415562-34-3
Fórmula molecular:C19H17ClF3N5O2
Pureza:95%+
Número de catálogo:CM577708
Peso molecular:439.82

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Detalles del producto

Núm. De CAS :1415562-34-3
Fórmula molecular:C19H17ClF3N5O2
Punto de fusión:-
Código de sonrisas:CC(=O)NCC(=O)N1[C@H]2CC[C@@H]1C1=C2C=CC(NC2=NC=C(C(Cl)=N2)C(F)(F)F)=C1
Densidad:
Número de catálogo:CM577708
Peso molecular:439.82
Punto de ebullición:
Nº Mdl:
Almacenamiento:

Category Infos

Pyrimidines
Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.
Bridged Compounds
Bridged ring compound refers to any two rings in the compound, which share two non-directly connected carbon atoms, and are classified into bicyclic hydrocarbons, tricyclic hydrocarbons, tetracyclic hydrocarbons, etc. Carbon atoms used in two or more rings are bridgehead carbon atoms, and the bond connecting the bridgehead carbon atoms is called a bridge. Bridged ring compounds are a class of organic compounds that are widely present in nature and usually have important physiological activities, such as the famous anticancer drug paclitaxel and antimalarial drug artemisinin.
bridged compounds,bridged bicyclic compounds
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Fluorinated Compounds
Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.