Nombre del producto:3-(Hydroxymethyl)oxetane-3-carbonitrile

IUPAC Name:3-(hydroxymethyl)oxetane-3-carbonitrile

CAS:1374657-44-9
Fórmula molecular:C5H7NO2
Pureza:95%+
Número de catálogo:CM284420
Peso molecular:113.12

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Detalles del producto

Núm. De CAS :1374657-44-9
Fórmula molecular:C5H7NO2
Punto de fusión:-
Código de sonrisas:N#CC1(CO)COC1
Densidad:
Número de catálogo:CM284420
Peso molecular:113.12
Punto de ebullición:
Nº Mdl:MFCD19103511
Almacenamiento:Keep in a dry and a tight container and store at ambient temperature

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Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.

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