Nombre del producto:2-chloro-4-cyano-6-fluoro-N-(2-((1R,2R)-2-fluorocyclopropanecarboxamido)pyridin-4-yl)benzamide

IUPAC Name:2-chloro-4-cyano-6-fluoro-N-{2-[(1R,2R)-2-fluorocyclopropaneamido]pyridin-4-yl}benzamide

CAS:1258294-34-6
Fórmula molecular:C17H11ClF2N4O2
Pureza:95%+
Número de catálogo:CM767107
Peso molecular:376.75

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Detalles del producto

Núm. De CAS :1258294-34-6
Fórmula molecular:C17H11ClF2N4O2
Punto de fusión:-
Código de sonrisas:F[C@@H]1C[C@@H]1C(=O)NC1=NC=CC(NC(=O)C2=C(Cl)C=C(C=C2F)C#N)=C1
Densidad:
Número de catálogo:CM767107
Peso molecular:376.75
Punto de ebullición:
Nº Mdl:MFCD28386356
Almacenamiento:

Category Infos

Pyridines
Pyridine is a six-membered heterocyclic compound containing one nitrogen heteroatom. Pyridine and piperidine are the most frequently occurring heterocyclic building blocks in drug molecules. According to incomplete statistics, there are currently more than 180 drugs containing pyridine or piperidine structure that have been marketed, nearly 1/5 of the drugs approved for marketing in recent years contain these two structures.
Pyridine | C5H5N | Pyridine Supplier/Distributor/Manufacturer - Chemenu
Pyridine,Pyridine Wholesale,Pyridine for Sale,Pyridine Supplier,Pyridine Distributor,Pyridine Manufacturer
Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell.
Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.