Nombre del producto:tert-butyl 6-amino-2-azaspiro[3.3]heptane-2-carboxylate

IUPAC Name:tert-butyl 6-amino-2-azaspiro[3.3]heptane-2-carboxylate

CAS:1211586-09-2
Fórmula molecular:C11H20N2O2
Pureza:95%
Número de catálogo:CM104296
Peso molecular:212.29

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Detalles del producto

Núm. De CAS :1211586-09-2
Fórmula molecular:C11H20N2O2
Punto de fusión:-
Código de sonrisas:CC(C)(C)OC(=O)N1CC2(CC(N)C2)C1
Densidad:
Número de catálogo:CM104296
Peso molecular:212.29
Punto de ebullición:
Nº Mdl:MFCD15071432
Almacenamiento:Keep in a dry and a tight container and store at 2°C~8°C

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Spiro Compounds
A spiro compound is a polycyclic compound in which two monocyclic rings share one carbon atom; the shared carbon atom is called a spiro atom. Spiro compounds have rigid structures, stable structures, and have special properties that general organic compounds do not possess, such as anomeric effect, spiro conjugation and spiro hyperconjugation. Compared with the monocyclic structure or the planar aromatic structure, the spiro structure has a larger three-dimensional structure; the heterocyclic spiro structure is also regarded as the biological isostere of some groups, which can change the drug to a certain extent. The water solubility, lipophilicity, dominant conformation and ADMET properties of the molecule make the optimized lead molecule easier to drug. Therefore, spiro compounds occupy a very important position in drug development.
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Azetidines
Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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Cyclobutanes
The molecular structure of cyclobutane has four carbon atoms, and its four carbon atoms are not in the same plane, which is the folded conformation of cyclobutane. Cyclobutane itself is not of commercial or biological interest, but more complex derivatives are important in biology and biotechnology. Currently, nine FDA-approved drugs contain the cyclobutane structure. From the perspective of therapeutic areas, cyclobutyl drugs are mainly distributed in popular areas such as tumors, neurological diseases, infectious diseases, endocrine and metabolic diseases.

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