Nombre del producto:(3-bromo-4-fluorophenyl)boronic acid
IUPAC Name:(3-bromo-4-fluorophenyl)boronic acid
Product Overview |
(3-bromo-4-fluorophenyl)boronic acid, also known as BFBPA, is an organic compound with a molecular formula of C6H5BBrFO2 that is used in synthetic organic chemistry. It is a colorless solid that is soluble in water and other organic solvents. BFBPA is used as a reagent in a variety of reactions, including Suzuki-Miyaura coupling, Sonogashira coupling, and Stille coupling. It is also used as a catalyst for the formation of arylboronic esters. |
Synthesis and Application |
The synthesis of (3-bromo-4-fluorophenyl)boronic acid can be achieved by reacting 4-fluorobenzaldehyde and 3-bromobenzene in the presence of a palladium catalyst and a base. The reaction proceeds via a palladium-catalyzed cross-coupling reaction to form the desired product. The reaction can be carried out in a variety of solvents, including acetonitrile, toluene, and dimethylformamide. (3-bromo-4-fluorophenyl)boronic acid is widely used in scientific research, as it can be used to synthesize a variety of compounds. It is especially useful in the synthesis of arylboronic esters, which are important intermediates in the synthesis of pharmaceuticals and other organic compounds. (3-bromo-4-fluorophenyl)boronic acid is also used in the synthesis of aryl fluorides, which are important building blocks for the synthesis of small molecules and materials. |
Future Directions |
There are a number of potential future directions for the use of (3-bromo-4-fluorophenyl)boronic acid in scientific research. One potential direction is the use of (3-bromo-4-fluorophenyl)boronic acid in the synthesis of complex molecules, such as peptides and proteins. In addition, (3-bromo-4-fluorophenyl)boronic acid could be used in the synthesis of new types of materials, such as polymers and nanomaterials. Finally, (3-bromo-4-fluorophenyl)boronic acid could be used in the development of new drugs, as it has been shown to have a variety of biochemical and physiological effects. |