Nombre del producto:(3-bromo-4-fluorophenyl)boronic acid

IUPAC Name:(3-bromo-4-fluorophenyl)boronic acid

CAS:1092533-91-9
Fórmula molecular:C6H5BBrFO2
Pureza:95%
Número de catálogo:CM121956
Peso molecular:218.82

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Detalles del producto

Núm. De CAS :1092533-91-9
Fórmula molecular:C6H5BBrFO2
Punto de fusión:-
Código de sonrisas:FC1=CC=C(B(O)O)C=C1Br
Densidad:
Número de catálogo:CM121956
Peso molecular:218.82
Punto de ebullición:
Nº Mdl:MFCD13195642
Almacenamiento:

Category Infos

Boronic Acids and Esters
Boronic acids and boronate esters are commonly used reagents in Suzuki–Miyaura coupling chemistry. Organoboron derivatives are common reagents for C–C bond formation, either through classical palladium-mediated transformations or through other newer coupling methods. Boronic esters and acids are potential intermediates in the manufacture of many active pharmaceutical ingredients (API).
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Benzenes
Benzene is an important organic compound with the chemical formula C6H6, and its molecule consists of a ring of 6 carbon atoms, each with 1 hydrogen atom. Benzene is a sweet, flammable, colorless and transparent liquid with carcinogenic toxicity at room temperature, and has a strong aromatic odor. It is insoluble in water, easily soluble in organic solvents, and can also be used as an organic solvent itself. The ring system of benzene is called benzene ring, and the structure after removing one hydrogen atom from the benzene ring is called phenyl. Benzene is one of the most important basic organic chemical raw materials. Many important chemical intermediates can be derived from benzene through substitution reaction, addition reaction and benzene ring cleavage reaction.

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Product Other Information

Product Overview (3-bromo-4-fluorophenyl)boronic acid, also known as BFBPA, is an organic compound with a molecular formula of C6H5BBrFO2 that is used in synthetic organic chemistry. It is a colorless solid that is soluble in water and other organic solvents. BFBPA is used as a reagent in a variety of reactions, including Suzuki-Miyaura coupling, Sonogashira coupling, and Stille coupling. It is also used as a catalyst for the formation of arylboronic esters.
Synthesis and Application The synthesis of (3-bromo-4-fluorophenyl)boronic acid can be achieved by reacting 4-fluorobenzaldehyde and 3-bromobenzene in the presence of a palladium catalyst and a base. The reaction proceeds via a palladium-catalyzed cross-coupling reaction to form the desired product. The reaction can be carried out in a variety of solvents, including acetonitrile, toluene, and dimethylformamide. (3-bromo-4-fluorophenyl)boronic acid is widely used in scientific research, as it can be used to synthesize a variety of compounds. It is especially useful in the synthesis of arylboronic esters, which are important intermediates in the synthesis of pharmaceuticals and other organic compounds. (3-bromo-4-fluorophenyl)boronic acid is also used in the synthesis of aryl fluorides, which are important building blocks for the synthesis of small molecules and materials.
Future Directions There are a number of potential future directions for the use of (3-bromo-4-fluorophenyl)boronic acid in scientific research. One potential direction is the use of (3-bromo-4-fluorophenyl)boronic acid in the synthesis of complex molecules, such as peptides and proteins. In addition, (3-bromo-4-fluorophenyl)boronic acid could be used in the synthesis of new types of materials, such as polymers and nanomaterials. Finally, (3-bromo-4-fluorophenyl)boronic acid could be used in the development of new drugs, as it has been shown to have a variety of biochemical and physiological effects.